BDBM50355497 AZD-6244::CHEMBL1614701

SMILES Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(cc12)C(=O)NOCCO

InChI Key InChIKey=CYOHGALHFOKKQC-UHFFFAOYSA-N

Data  7 IC50  442 Kd

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355497   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for SRC kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed